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To evaluate the healing efficacy, a comprehensive experiment was conducted on diabetic wounds treated with various agents, including: i) PBS as negative control (NC group), ii) ROS-responsive hydrogel matrix (G group), iii) monomer copper peptides M-CuP solution (M-CuP group), iv) dimeric copper peptides D-CuP solution (D-CuP group), v) ROS-responsive hydrogel with monomer copper peptides M-CuP (G/M-CuP group), and vi) ROS-responsive hydrogel with dimeric copper peptides (G/D-CuP group)

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MOTS-c levels were observed to correlate with endothelial function markers in research, with treatment datasets showing measurement shifts in vascular signaling